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Merck
CN

915033

TissueFab® bioink Bone

Vis/405 nm

Synonym(s):

3D Bioprinting, Bioink, GelMA, TissueFab

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About This Item

NACRES:
NA.23
UNSPSC Code:
12352201
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Quality Level

description

0.2 μm sterile filtered, suitable for 3D bioprinting applications

form

gel form (viscous)

impurities

≤5 CFU/g Bioburden (Fungal), ≤5 CFU/g Bioburden (Total Aerobic)

color

white

pH

6.5-7.5

application(s)

3D bioprinting

storage temp.

2-8°C

Application

TissueFab® - GelMA-Bone-Vis bioink is designed for promoting osteogenic differentiation of stem cells. It is based on Gelatin methacryloyl (GelMA) - Hydroxyapatite (HAp) hydrogel system. HAp is a highly crystalline form of calcium phosphate. HAp has a chemical similarity with the mineralized phase of bone which accounts for their excellent biocompatibility and osteoinductive and osteoconductive properties favorable for bone regeneration. HAp-containing hydrogels has been studied in literature to demonstrate their processability with different additive manufacturing approaches. Printing of cell laden structures with HAp containing bioink formulations have shown superior osteogenic properties.

Packaging

Product contains 10 ml of solution packaged in glass bottle.

Legal Information

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

Regulatory Information

低风险生物材料

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Articles

生物墨水可3D生物打印形成功能组织结构,从而应用于药物筛选、疾病建模和体外移植。针对特定组织工程应用选择生物墨水和打印方法。

Bioinks enable 3D bioprinting of tissue constructs for drug screening and transplantation; select suitable bioinks for specific tissue engineering.

Learn how 3D bioprinting is revolutionizing drug discovery with highly-controllable cell co-culture, printable biomaterials, and its potential to simulate tissues and organs. This review paper also compares 3D bioprinting to other advanced biomimetic techniques such as organoids and organ chips.

Related Content


Tunable hydrogel composite with two-step processing in combination with innovative hardware upgrade for cell-based threedimensional bioprinting.
Wust S. et al.
Acta Biomaterialia, 10, 630-640 (2014)
Nano hydroxyapatite particles promote osteogenesis in a three-dimensional bio-printing construct consisting of alginate/gelatin/hASCs
Wang X F et al.
Royal Society of Chemistry Advances, 6, 6832-6842 (2016)
Michal Bartnikowski et al.
Materials (Basel, Switzerland), 9(4) (2016-04-14)
The concept of biphasic or multi-layered compound scaffolds has been explored within numerous studies in the context of cartilage and osteochondral regeneration. To date, no system has been identified that stands out in terms of superior chondrogenesis, osteogenesis or the



Global Trade Item Number

SKUGTIN
915033-1EA04061842138418