Skip to Content
Merck
CN

918946

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)

PEG average Mn 5000, PDLLA average Mn 20000

Synonym(s):

Biodegradable, Block copolymer, Drug delivery, PEG-PLA, PLLA, mPEG-PLA, mPEG-PLLA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
HO[CH(CH3)COO]m[CH2CH2O]nCH3
NACRES:
NA.23
UNSPSC Code:
12352106
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


form

powder or chunks

Quality Level

mol wt

PDLA average Mn 20,000 (by NMR), PDLLA average Mn 20000, PEG average Mn 5,000 (by NMR), PEG average Mn 5000

color

white to beige

storage temp.

2-8°C

Application

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide) is an amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block.These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics).


Still not finding the right product?


Storage Class

11 - Combustible Solids

wgk

WGK 3



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these



Global Trade Item Number

SKUGTIN
918946-500G04065265243384
918946-500MG04065265940962