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Merck
CN

922188

Low endotoxin GelMA

bloom 300, Type A, degree of substitution 80%

Synonym(s):

3D Bioprinting, GelMA, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl, Gelatin / GelMA & derivatives

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About This Item

NACRES:
NA.23
UNSPSC Code:
12352202
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Quality Level

form

powder or chunks

impurities

<10 CFU/g Bioburden, <125 EU/g Endotoxin

color

white to off-white

storage temp.

2-8°C

Application

This is a low endotoxin GelMA for use in biomedical research applications.
GelMA can be used to form hydrogels for tissue engineering and 3D bioprinting. Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.

Packaging

500 mg in glass bottle


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Photocrosslinkable gelatin hydrogel for epidermal tissue engineering.
Zhao X, Khademhosseini A
Advanced Helathcare Materials (2015)
Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide
Gupta NV et al.
Indian journal of pharmacy and pharmacology, 69(1, 64-68 (2007)
Anh H Nguyen et al.
Acta biomaterialia, 13, 101-110 (2014-12-03)
Gelatin has been commonly used as a delivery vehicle for various biomolecules for tissue engineering and regenerative medicine applications due to its simple fabrication methods, inherent electrostatic binding properties, and proteolytic degradability. Compared to traditional chemical cross-linking methods, such as



Global Trade Item Number

SKUGTIN
922188-1EA04065266707816