927600
BrBT-alkyne
≥95%
Synonym(s):
2-Bromo-N-(prop-2-yn-1-yl)benzo[d]thiazole-6-carboxamide
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C11H7BrN2OS
CAS Number:
Molecular Weight:
295.16
MDL number:
UNSPSC Code:
12352101
NACRES:
NA.22
Quality Level
assay
≥95%
form
powder
storage temp.
−20°C
SMILES string
BrC1=NC2=CC=C(C(NCC#C)=O)C=C2S1
InChI
1S/C11H7BrN2OS/c1-2-5-13-10(15)7-3-4-8-9(6-7)16-11(12)14-8/h1,3-4,6H,5H2,(H,13,15)
InChI key
MRYSQSUDZPBHGP-UHFFFAOYSA-N
Application
BrBT-alkyne is a probe that can be used to lable cysteines through nucleophilic aromatic substitution. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitave applications (Zanon et al. 2021). The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis (Zanon et al. 2020). Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow (Weerapana et al. 2010, Backus et al. 2016).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Isotopically Labeled Desthiobiotin Azide (isoDTB) Tags Enable Global Profiling of the Bacterial Cysteinome.
Zanon P R A, et al.
Angewandte Chemie (International Edition in English), 2829-2836 (2020)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 927600-50MG | 04065268032183 |