927821
EBX2-alkyne
≥95%
Synonym(s):
5-Methyl-1-((trimethylsilyl)ethynyl)-1l3-benzo[d][1,2]iodaoxol-3(1H)-one
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About This Item
Empirical Formula (Hill Notation):
C13H15IO2Si
CAS Number:
Molecular Weight:
358.25
MDL number:
UNSPSC Code:
12352101
NACRES:
NA.22
Assay:
≥95%
Form:
powder
Quality Level
assay
≥95%
form
powder
storage temp.
−20°C
SMILES string
CC1=CC(C(OI2C#C[Si](C)(C)C)=O)=C2C=C1
InChI
1S/C13H15IO2Si/c1-10-5-6-12-11(9-10)13(15)16-14(12)7-8-17(2,3)4/h5-6,9H,1-4H3
InChI key
MJEDSBVZRIKHTM-UHFFFAOYSA-N
Application
EBX2-alkyne is a hypervalent iodine reagent used for labeling cysteines. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitative applications . The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis . Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow .
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 927821-50MG | 04065268233498 |