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943401

1-(6-Bromo-1-methylindazol-3-yl)hexahydropyrimidine-2,4-dione

≥95%

Synonym(s):

(6-Bromo-1-methylindazol-3-yl)-1,3-diazinan-2,4-dione, 1-(6-Bromo-1-methyl-1H-indazol-3-yl)dihydro-2,4(1H,3H)-pyrimidinedione, 1-(6-Bromo-1-methylindazol-3-yl)-1,3-diazinane-2,4-dione, 2,4(1H,3H)-Pyrimidinedione, 1-(6-bromo-1-methyl-1H-indazol-3-yl)dihydro-

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About This Item

Empirical Formula (Hill Notation):
C12H11BrN4O2
CAS Number:
2446913-88-6
Molecular Weight:
323.15
MDL number:
MFCD35084702
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Quality Level

100

description

Reaction suitability: A functionalized CRBN ligand for development of small molecule degraders

assay

≥95%

form

amorphous solid

color

pale yellow to beige

functional group

(Bromide functionality for incorporating linker)

storage temp.

2-8°C

SMILES string

O=C1NC(CCN1C2=NN(C)C3=C2C=CC(Br)=C3)=O

InChI

InChI=1S/C12H11BrN4O2/c1-16-9-6-7(13)2-3-8(9)11(15-16)17-5-4-10(18)14-12(17)19/h2-3,6H,4-5H2,1H3,(H,14,18,19)

InChI key

FVEJZRXMQPIZQZ-UHFFFAOYSA-N

General description

This compound is a dihydropyrimidine-dione derivative, featuring an indazole ring substituted with a bromine and a methyl group, linked to a dihydropyrimidinedione moiety.

Application

A functionalized CRBN ligand for synthesis of small molecule degraders.

Features and Benefits

Bromide functionality is useful for incorporating linker for choice for degrader diversity.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Global Trade Item Number

SKUGTIN
943401-1G04065273608090