A71328
4-Aminophenol
≥98%
Synonym(s):
4-Hydroxyaniline
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About This Item
Linear Formula:
H2NC6H4OH
CAS Number:
Molecular Weight:
109.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-616-2
Beilstein/REAXYS Number:
385836
MDL number:
Assay:
≥98%
Form:
granular, powder or crystals
Quality Level
assay
≥98%
form
granular, powder or crystals
mp
185-189 °C (lit.)
solubility
water: slightly soluble
SMILES string
Nc1ccc(O)cc1
InChI
1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
InChI key
PLIKAWJENQZMHA-UHFFFAOYSA-N
General description
4-Aminophenol (4-Hydroxyaniline) is an organic building block. Its quantification in water samples upto the detection limit of 8×10-10mol l-1 has been proposed by employing single-wall carbon nanotubes (SWNT)-nafion film coated glassy carbon electrodes. It is present as the main contaminant in pharmaceutical formulations of paracetamol. High-performance liquid chromatographic (HPLC) method with amperometric detection has been reported for its determination in various analgesic formulations. It has been reported to be formed from the reduction of 4-nitrophenol (Nip) under metal-free conditions catalyzed by N-doped graphene (NG).
Application
4-Aminophenol is suitable for use in the synthesis of 2,2-bis(4-aminophenoxy) benzonitrile [4-APBN], a monomer required for the preparation of series of polyamides and poly(amide-imide)s. It may be used as derivatization reagent to improve the ionization of aliphatic and aromatic aldehydes by paper spray ionization mass spectrometry.
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signalword
Warning
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2
target_organs
Kidney
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
危险化学品
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Saxena A, et al.
Eur. Polymer J., 39(2), 401-405 (2003)
Metal-free catalytic reduction of 4-nitrophenol to 4-aminophenol by N-doped graphene.
Kong XK, et al.
Energy & Environmental Science, 6(11), 3260-3266 (2013)
Wensheng Huang et al.
Talanta, 61(3), 411-416 (2008-10-31)
A single-wall carbon nanotubes (SWNT)-Nafion film coated glassy carbon electrode (GCE) was described for the determination of 4-aminophenol. In pH 3.0 sodium citrate-HCl buffer, the oxidation peak current of 4-aminophenol increases greatly at the SWNT-Nafion film coated GCE in contrast
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A71328-5G | 04061833383667 |
| A71328-100G | 04061833383636 |
| A71328-1KG | 04061833383643 |
| A71328-500G | 04061833383650 |