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Merck
CN

A9563

4-Aminophenylmercuric acetate

≥90% (titration)

Synonym(s):

4-(Acetoxymercurio)aniline, APMA

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About This Item

Linear Formula:
CH3CO2HgC6H4NH2
CAS Number:
Molecular Weight:
351.75
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
228-497-1
Beilstein/REAXYS Number:
3664749
MDL number:
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Quality Level

assay

≥90% (titration)

form

powder

mp

163-165 °C (lit.)

solubility

DMSO: soluble 10 mg/mL, H2O: soluble 5 mM, glacial acetic acid: soluble 50 mg/mL

SMILES string

CC(=O)O[Hg]c1ccc(N)cc1

InChI

1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1

InChI key

RXSUFCOOZSGWSW-UHFFFAOYSA-M

Biochem/physiol Actions

An organomercurial activator of matrix metalloproteinases.

Disclaimer

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.


signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Manuel Johanns et al.
Scientific reports, 7(1), 4328-4328 (2017-07-01)
Matrix metalloproteinases (MMPs) are regulated at multiple transcriptional and post-transcriptional levels, among which receptor-mediated endocytic clearance. We previously showed that low-density lipoprotein receptor-related protein-1 (LRP-1) mediates the clearance of a complex between the zymogen form of MMP-2 (proMMP-2) and tissue
K R French et al.
Equine veterinary journal, 36(3), 261-266 (2004-05-19)
Acute laminitis is characterised by hoof lamellar dermal-epidermal separation at the basement membrane (BM) zone. Hoof lamellar explants cultured in vitro can also be made to separate at the basement membrane zone and investigating how this occurs may give insight
Nian-Qiu Shi et al.
International journal of nanomedicine, 7, 1613-1621 (2012-05-24)
The use of activable cell-penetrating peptides (ACPPs) as molecular imaging probes is a promising new approach for the visualization of enzymes. The cell-penetrating function of a polycationic cell-penetrating peptide (CPP) is efficiently blocked by intramolecular electrostatic interactions with a polyanionic



Global Trade Item Number

SKUGTIN
A9563-5G04061833403570
A9563-1G04061824071207
A9563-25G04061833403556