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Merck
CN

C4790

Carbenoxolone disodium salt

≥98%

Synonym(s):

3β-Hydroxy-11-oxoolean-12-en-30-oic acid 3-hemisuccinate

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About This Item

Linear Formula:
C34H48O7Na2
CAS Number:
Molecular Weight:
614.72
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352108
EC Number:
231-044-0
MDL number:
Assay:
≥98%
Form:
powder
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Quality Level

assay

≥98%

form

powder

storage temp.

2-8°C

SMILES string

[Na].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)[C@]4([H])[C@@]5(C)CC[C@H](OC(=O)CCC(O)=O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O

InChI

1S/C34H50O7.2Na/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6;;/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40);;/q;2*+1/p-2/t21-,23?,24-,27+,30+,31?,32-,33+,34+;;/m0../s1

InChI key

BQENDLAVTKRQMS-FDPMUVMVSA-L

General description

Carbenoxolone disodium is a water soluble disodium salt of glycyrrhetinic acid hemisuccinate. It acts as an efficient promoter for the nasal absorption of insulin.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Ashwin Miriyala et al.
Current biology : CB, 28(10), 1585-1594 (2018-05-15)
Animals detect changes in the environment using modality-specific, peripheral sensory neurons. The insect gustatory system encodes tastant identity and concentration through the independent firing of gustatory receptor neurons (GRNs) that spike rapidly at stimulus onset and quickly adapt. Here, we
Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I.
Mishima M, et al.
Journal of Pharmacobio-Dynamics, 12(1), 31-36 (1989)
R A Warwick et al.
European journal of pain (London, England), 17(4), 571-580 (2012-10-16)
Chemotherapy-induced peripheral neuropathy is a serious side effect in cancer treatment, a major manifestation being neuropathic pain that can be debilitating and can reduce the quality of life of the patient. Oxaliplatin and taxol are common anti-cancer drugs that induce



Global Trade Item Number

SKUGTIN
C4790-1G04061833492925
C4790-5G04061833492932