C85778
o-Cresolphthalein
Indicator grade, powder
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About This Item
Empirical Formula (Hill Notation):
C22H18O4
CAS Number:
Molecular Weight:
346.38
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
209-881-8
MDL number:
Beilstein/REAXYS Number:
310554
Product Name
o-Cresolphthalein, indicator grade
grade
indicator grade
Quality Level
form
powder
technique(s)
titration: suitable
color
beige
pH
8.2-9.8, colorless to red
mp
219-221 °C (lit.)
λmax
381 nm (2nd), 566 nm
ε (extinction coefficient)
≥10000 at 294-300 nm, ≥39000 at 564-570 nm, ≥5000 at 378-384 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Cc1cc(ccc1O)C2(OC(=O)c3ccccc23)c4ccc(O)c(C)c4
InChI
1S/C22H18O4/c1-13-11-15(7-9-19(13)23)22(16-8-10-20(24)14(2)12-16)18-6-4-3-5-17(18)21(25)26-22/h3-12,23-24H,1-2H3
InChI key
CPBJMKMKNCRKQB-UHFFFAOYSA-N
Application
O-Cresolphthalein has been used as a component in calcifying media for calcification assay.
Biochem/physiol Actions
o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Hyunseok Peter Kang et al.
Clinical chemistry, 50(4), 741-746 (2004-02-14)
Gadolinium formulations, which are administered as contrast agents in magnetic resonance imaging examinations, interfere with colorimetric serum calcium determinations. We performed an in vitro study to determine the extent to which three gadolinium formulations-gadodiamide (Omniscan), gadopentetate dimeglumine (Magnevist), and gadoversetamide
Jin-Hyun Kim et al.
PloS one, 14(4), e0215244-e0215244 (2019-04-17)
In the stratum corneum, the intercellular junction made up of cadherin proteins provides the structural integrity of the framework. Ca2+ ions are known to play a key role in maintaining this junction. In this study, we hypothesized that Ca2+ chelation
J E Van Nuwenborg et al.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 35(4), 297-300 (1997-04-01)
We evaluated bias and inaccuracy of four frequently used routine test systems for serum total calcium, using a candidate reference method based on ion chromatography. The mean biases and 95% confidence intervals that we observed were 0.0 +/- 0.59% for
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C85778-10G | 04061833522578 |