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D161403

5,5-Dimethylhydantoin

Name: 5,5-Dimethylhydantoin
Brand: ALDRICH

97%

Synonym(s):

Fennosurf 300, 4,4-Dimethyl-2,5-dioxoimidazolidine, DMH

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About This Item

Empirical Formula (Hill Notation):

C₅H₈N₂O₂

CAS Number:

77-71-4

Molecular Weight:

128.13

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24893496

EC Number:

201-051-3

Beilstein/REAXYS Number:

2827

MDL number:

MFCD00005266

Assay:

97%

Form:

crystals

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Properties

Quality Level

200

assay

97%

form

crystals

mp

174-177 °C (lit.)

SMILES string

CC1(C)NC(=O)NC1=O

InChI

1S/C5H8N2O2/c1-5(2)3(8)6-4(9)7-5/h1-2H3,(H2,6,7,8,9)

InChI key

YIROYDNZEPTFOL-UHFFFAOYSA-N

Description

Application

Reactant for synthesis of:

N-chloroheterocyclic antimicrobials
β-Amino alcohols as inhibitors of antitubercular target N-acetyltransferase
Second-generation selective inhibitors of hepatitis C virus NS3 serine protease
Rechargeable biocidal cellulose
N-chlorohydantoins

Reactant for asymmetric chlorolactonization reactions

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposity.

Shin J Lee et al.

Molecular metabolism, 11, 33-46 (2018-04-14)

Glucagon-like peptide-1 (GLP-1) neurons in the hindbrain densely innervate the dorsomedial hypothalamus (DMH), a nucleus strongly implicated in body weight regulation and the sympathetic control of brown adipose tissue (BAT) thermogenesis. Therefore, DMH GLP-1 receptors (GLP-1R) are well placed to

Ameliorative effects of pyrazinoic acid against oxidative and metabolic stress manifested in rats with dimethylhydrazine induced colonic carcinoma.

Anil K Sahdev et al.

Cancer biology & therapy, 18(5), 304-313 (2017-03-31)

Pyrazinoic acid (PA) is structurally similar to nicotinic acid which acts on G-protein-coupled receptor (GPR109A). GPR109A expresses in colonic and intestinal epithelial sites, and involves in DNA methylation and cellular apoptosis. Therefore, it may be assumed that PA has similar

Antimicrobial N-halamine modified chitosan films.

Rong Li et al.

Carbohydrate polymers, 92(1), 534-539 (2012-12-12)

The inherent antimicrobial properties and biodegradability of chitosan make it an ideal candidate for antimicrobial materials. In this study, N-halamine precursor 3-glycidyl-5,5-dimethylhydantoin (GH) was synthesized and bonded onto chitosan by a ring opening reaction between chitosan and GH. The chitosan

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Global Trade Item Number

SKU	GTIN
D161403-100G	04061833560297
D161403-1KG	04061826738290