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D199303

2,4-Dinitrophenylhydrazine

Name: 2,4-Dinitrophenylhydrazine
Brand: ALDRICH

reagent grade, 97%, suitable for analytical testing

Synonym(s):

(2,4-dinitrophenyl)-hydrazine, DNPH

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About This Item

Linear Formula:

(O₂N)₂C₆H₃NHNH₂

CAS Number:

119-26-6

Molecular Weight:

198.14

NACRES:

NA.21

PubChem Substance ID:

24893586

UNSPSC Code:

12352100

MDL number:

MFCD00007578

Beilstein/REAXYS Number:

615586

Assay:

97%

Grade:

reagent grade

Technique(s):

HPLC: suitable (for analytical testing)

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Properties

Product Name

2,4-Dinitrophenylhydrazine, reagent grade, 97%

grade

reagent grade

Quality Level

200

assay

97%

contains

33% water (minimum)

technique(s)

HPLC: suitable (for analytical testing)

mp

197-200 °C (lit.)

functional group

hydrazine, nitro

SMILES string

NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2

InChI key

HORQAOAYAYGIBM-UHFFFAOYSA-N

Description

General description

2,4-Dinitrophenylhydrazine (DNPH), a hydrazine derivative, is a potential mutagenic agent. Its molecular and crystal structure has been analyzed. The intra- and intermolecular hydrogen bonds in DNPH have been investigated by vibrational spectroscopic analysis. The mechanism of isothermal degradation of DNPH has been studied by differential scanning calorimetry (DSC).

Application

2,4-Dinitrophenylhydrazine has been used as a reagent to detect the presence of aldehydes and ketones in protein carbonyls. It may be used as a colorimetric reagent in the quantitative estimation of prednisone.

Packaging

500G contains total wet product weight of ~485G. Variance is due to addition of water to meet DOT requirements.

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pictograms

GHS02,GHS07

signalword

Danger

hcodes

H206,H302

pcodes

P210 - P212 - P230 - P233 - P280 - P370 + P380 + P375 - P501

Hazard Classifications

Acute Tox. 4 Oral - Desen. Expl. 1

supp_hazards

EUH044

Storage Class

4.1A - Other explosive hazardous materials

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data.

Xianglu Han et al.

Toxicology, 297(1-3), 1-9 (2012-04-11)

There is an urgent need for in vitro screening assays to evaluate nanoparticle (NP) toxicity. However, the relevance of in vitro assays is still disputable. We administered doses of TiO(2) NPs of different sizes to alveolar epithelial cells in vitro

2,4-dinitrophenylhydrazine: a sensitive quantitative reagent for determining microgram quantities of prednisone.

A L Woodson

Journal of pharmaceutical sciences, 60(10), 1538-1542 (1971-10-01)

Indian J. Chem. B, 32, 986-986 (1993)

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Global Trade Item Number

SKU	GTIN
D199303-500G	04061835253135
D199303-100G	04061835253111
D199303-25G	04061835253128