L1002
L-Leucine methyl ester hydrochloride
98%, for peptide synthesis
Synonym(s):
(S)-2-Amino-4-methylpentanoic acid methyl ester hydrochloride, L-Leu-OMe·HCl
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About This Item
Linear Formula:
(CH3)2CHCH2CH(NH2)COOCH3 · HCl
CAS Number:
Molecular Weight:
181.66
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
231-375-0
MDL number:
Beilstein/REAXYS Number:
3595133
Product Name
L-Leucine methyl ester hydrochloride, 98%
Quality Level
assay
98%
form
powder or crystals
optical activity
[α]22/D +13°, c = 2 in H2O
reaction suitability
reaction type: solution phase peptide synthesis
color
white
mp
151-153 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl[H].COC(=O)[C@@H](N)CC(C)C
InChI
1S/C7H15NO2.ClH/c1-5(2)4-6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t6-;/m0./s1
InChI key
DODCBMODXGJOKD-RGMNGODLSA-N
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Gautam K Gandhi et al.
ASN neuro, 2(2), e00030-e00030 (2010-04-17)
Sensory and cognitive impairments have been documented in diabetic humans and animals, but the pathophysiology of diabetes in the central nervous system is poorly understood. Because a high glucose level disrupts gap junctional communication in various cell types and astrocytes
Kenneth W Kross et al.
Acta oto-laryngologica, 127(5), 532-539 (2007-04-25)
Conclusion. Tumour-associated macrophages (TAMs) in head and neck squamous cell carcinomas (HNSCCs) secrete interleukin 6 (IL-6) and monocyte chemotactic protein (MCP-1) that can be down-regulated by L-leucine-methylester (LLME); however, there is no qualitative difference between function of TAMs and tissue
Stephanie M Krasnow et al.
Journal of neuroinflammation, 14(1), 133-133 (2017-07-03)
During acute infections and chronic illnesses, the pro-inflammatory cytokine interleukin-1β (IL-1β) acts within the brain to elicit metabolic derangements and sickness behaviors. It is unknown which cells in the brain are the proximal targets for IL-1β with respect to the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L1002-25G | 04061833949122 |
| L1002-10G | 04061833949115 |