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Merck
CN

M5801

3-Mercaptopropionic acid

≥99%

Synonym(s):

3-sulfanylpropanoic acid

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About This Item

Linear Formula:
HSCH2CH2CO2H
CAS Number:
Molecular Weight:
106.14
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-537-0
Beilstein/REAXYS Number:
773807
MDL number:
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vapor pressure

0.04 mmHg ( 20 °C)

Quality Level

assay

≥99%

form

liquid

autoignition temp.

662 °F

refractive index

n20/D 1.492 (lit.)

bp

110-111 °C/15 mmHg (lit.)

mp

15-18 °C (lit.)

density

1.218 g/mL at 25 °C (lit.)

SMILES string

OC(=O)CCS

InChI

1S/C3H6O2S/c4-3(5)1-2-6/h6H,1-2H2,(H,4,5)

InChI key

DKIDEFUBRARXTE-UHFFFAOYSA-N

General description

3-Mercaptopropionic acid (3-MPA) is used as a self-assembled monolayer (SAM) with a thiol and carboxylic groups. It has short carbon chains and is mainly used as a capping agent on a variety of nanoparticles.

Application

3-MPA is used to produce hydrophilic SAMs, which are terminated with carboxylic acids and can be further functionalized to introduce more complex end groups such as enzymes for biosensor applications. SAMs of 3-MPA are capped on ZnSe quantum dots for the electrochemical detection of dopamine. 3-MPA is used as a capping agent on CdTe quantum dot nanocrystals (QD NCs) for use as labeling materials in biomedical applications. It can also be used to modify the surface of iron oxide nanoparticles (Fe2O3) in the extraction and preconcentration of Al3+ and Cr3+ ions from different biological samples.


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pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

200.1 °F - closed cup

flash_point_c

93.4 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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Articles

Professor Aran discusses engineering graphene-based materials through careful functionalization, enabling diverse applications.


Atomic absorption spectrometric determination of Al3+ and Cr3+ after preconcentration and separation on 3-mercaptopropionic acid modified silica coated-Fe3O4 nanoparticles.
Mashhadizadeh MH and Amoli-Diva M
Journal of Analytical Atomic Spectrometry, 28(2), 251-258 (2013)
A potential masking approach in the detection of dopamine on 3-mercaptopropionic acid capped ZnSe quantum dots modified gold electrode in the presence of interferences.
Ndangili PM, et al.
Journal of Electroanalytical Chemistry, 643(1-2), 77-81 (2010)
Coating aqueous quantum dots with silica via reverse microemulsion method: toward size-controllable and robust fluorescent nanoparticles.
Yang Y, et al.
Chemistry of Materials, 19(17), 4123-4128 (2007)



Global Trade Item Number

SKUGTIN
M5801-100G04061837489341
M5801-500G04061837489358
M5801-5G04061837489365