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P19809

2-Phenylbenzimidazole

Name: 2-Phenylbenzimidazole
Brand: ALDRICH

97%

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₀N₂

CAS Number:

716-79-0

Molecular Weight:

194.23

PubChem Substance ID:

24898258

eCl@ss:

32151902

UNSPSC Code:

12352100

NACRES:

NA.22

EC Number:

211-939-2

MDL number:

MFCD00005592

Assay:

97%

Form:

solid

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Properties

Quality Level

100

assay

97%

form

solid

mp

293-296 °C (lit.)

SMILES string

c1ccc(cc1)-c2nc3ccccc3[nH]2

InChI

1S/C13H10N2/c1-2-6-10(7-3-1)13-14-11-8-4-5-9-12(11)15-13/h1-9H,(H,14,15)

InChI key

DWYHDSLIWMUSOO-UHFFFAOYSA-N

Gene Information

human ... FGFR1(2260), PDGFRB(5159)

Description

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H315,H318,H335

pcodes

P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Light-induced cytotoxicity and genotoxicity of a sunscreen agent, 2-phenylbenzimidazole in Salmonella typhimurium TA 102 and HaCaT keratinocytes.

Charity N Mosley et al.

International journal of environmental research and public health, 4(2), 126-131 (2007-07-10)

2-phenylbenzimidazole (PBI) is an ingredient found in sunscreen agents. PBI can absorb the UV portion of the solar light and undergo a series of light-induced reactions to cause adverse effects in humans. Therefore, chemical and photochemical toxicity of PBI were

Substituted 2-phenyl-benzimidazole derivatives: novel compounds that suppress key markers of allergy.

Mark L Richards et al.

European journal of medicinal chemistry, 41(8), 950-969 (2006-05-02)

The pharmacotherapy of allergy and asthma has traditionally focused on the effecter molecules of the allergic cascade, while neglecting targets that play an early role in their development. Reasoning that IgE is central to the expansion of atopic diseases, we

Photosensitization of guanine-specific DNA damage by 2-phenylbenzimidazole and the sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid.

C Stevenson et al.

Chemical research in toxicology, 12(1), 38-45 (1999-01-20)

Gel sequencing experiments with end-labeled synthetic oligodeoxyribonucleotides have established that 2-phenylbenzimidazole (PBZ) and the common sunscreen constituent 2-phenylbenzimidazole-5-sulfonic acid (PBSA) function as efficient photosensitizers of DNA damage when they are exposed to UV-B (290-320 nm) radiation or natural sunlight. Although

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Global Trade Item Number

SKU	GTIN
P19809-5G	04061833327715