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T45802

2,4,6-Triaminopyrimidine

Name: 2,4,6-Triaminopyrimidine
Brand: ALDRICH

97%

Synonym(s):

2,4,6-Pyrimidinetriamine

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About This Item

Empirical Formula (Hill Notation):

C₄H₇N₅

CAS Number:

1004-38-2

Molecular Weight:

125.13

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24900218

EC Number:

213-720-7

Beilstein/REAXYS Number:

118448

MDL number:

MFCD00006100

Assay:

97%

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Properties

Quality Level

100

assay

97%

mp

249-251 °C (lit.)

SMILES string

Nc1cc(N)nc(N)n1

InChI

1S/C4H7N5/c5-2-1-3(6)9-4(7)8-2/h1H,(H6,5,6,7,8,9)

InChI key

JTTIOYHBNXDJOD-UHFFFAOYSA-N

Description

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Km and kcat. values for [6,6,7,7-2H]7,8(6H)-dihydropterin and 2,6-diamino-5-iminopyrimidin-4-one with dihydropteridine reductase.

W L Armarego et al.

The Biochemical journal, 211(2), 357-361 (1983-05-01)

The Km and kcat. values for [6,6,7,7-2H]7,8(6H)-dihydropterin and 2,6-diamino-5-iminopyrimidin-4-one were determined for dihydropteridine reductase (EC 1.6.99.10) from two sources. The parameters of the pterin are of the same order as those of the most effective substrates of dihydropteridine reductase. The

Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.

R Soni et al.

Journal of the National Cancer Institute, 93(6), 436-446 (2001-03-22)

Cyclin-dependent kinase 4 (Cdk4) represents a prime target for the treatment of cancer because most human cancers are characterized by overexpression of its activating partner cyclin D1, loss of the natural Cdk4-specific inhibitor p16, or mutation(s) in Cdk4's catalytic subunit.

Aluminum uptake by the in situ rat gut preparation.

S D Provan et al.

The Journal of pharmacology and experimental therapeutics, 245(3), 928-931 (1988-06-01)

An in situ rat gut preparation was used to elucidate the mechanisms of gastrointestinal aluminum (Al) absorption. Al uptake rate at the mucosal surface was decreased by the paracellular pathway blockers kinetin (1 mM) and 2,4,6-triaminopyrimidinium (10 mM), by sodium

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Global Trade Item Number

SKU	GTIN
T45802-25G	04061832919416