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W291706

Polysorbate 80

FG

Synonym(s):

TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

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About This Item

CAS Number:
9005-65-6
FEMA Number:
2917
UNSPSC Code:
12164502
E Number:
E 433
NACRES:
NA.21
MDL number:
MFCD00082107
Organoleptic:
alcohol
Grade:
FG, Halal, Kosher
Biological source:
palm oil, synthetic
Food allergen:
corn
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Quality Level

300, 400

biological source

palm oil, synthetic

grade

FG, Halal, Kosher

reg. compliance

EU Regulation 1333/2008 & 178/2002, FDA 21 CFR 172.515, FDA 21 CFR 172.836, FDA 21 CFR 172.838, FDA 21 CFR 172.840, FDA 21 CFR 172.842

vapor pressure

<1 mmHg ( 20 °C)

refractive index

n20/D 1.472 (lit.)

density

1.064 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

corn

organoleptic

alcohol

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

General description

Polysorbate 80 (TWEEN® 80) is a polyethylene sorbitol ester.

Application

Polysorbate 80 (TWEEN® 80), a hydrophilic non-ionic surfactant, is widely employed as a surfactant and solubilizing agent in food and cosmetic industries.

Legal Information

TWEEN is a registered trademark of Croda International PLC

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
STBK3065
STBK2536
STBK1637
STBJ9699
MKBJ0197V

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Stability characterization of a polysorbate 80-dimethyl trisulfide formulation, a cyanide antidote candidate.
Bartling CM, et al.
Drugs in R&D, 16(1), 109-127 (2016)
Use of Polysorbate 80 (Tween 80) as a phase-transfer catalyst.
Thoman CJ, et al.
The Journal of Organic Chemistry, 54(18), 4476-4478 (1989)
Hongjian Zhang et al.
Archives of pharmacal research, 26(9), 768-772 (2003-10-17)
Tween 80 (Polysorbate 80) is a hydrophilic nonionic surfactant commonly used as an ingredient in dosing vehicles for pre-clinical in vivo studies (e.g., pharmacokinetic studies, etc.). Tween 80 increased apical to basolateral permeability of digoxin in Caco-2 cells suggesting that
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Global Trade Item Number

SKUGTIN
W291706-1KG-K04061837545887
W291706-25KG-K04061837545894
W291706-10KG-K04061837545870
W291706-SAMPLE-K04061837545900