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About This Item
Empirical Formula (Hill Notation):
C43H69D7O2
CAS Number:
Molecular Weight:
632.11
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141804
Assay:
>99% (TLC)
Form:
powder
Product Name
16:0 cholesteryl-d7 ester, Avanti Research™ - A Croda Brand 700149P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (700149P-10mg), pkg of 1 × 25 mg (700149P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700149P
shipped in
dry ice
storage temp.
−20°C
General description
Cholesteryl palmitate is a cholesteryl ester. 16:0 cholesteryl-d7 ester is the deuterated form of cholesteryl palmitate or 16:0 cholesteryl ester.
Application
16:0 cholesteryl-d7 ester has been used:
- in plasma sample preparation for tandem mass spectrometry analysis (MS/MS)
- as an internal standard in mass spectrometry for quantification of nerve lipids from mice
- as an internal standard in time-of-flight mass spectrometry (TOFMS) for the quantification of serum extracellular vesicles (EVs) lipids
- as an external calibrator and internal spiking standard in tandem mass spectroscopy measurements
- in liposome preparation for retinyl ester hydrolase (REH) and cholesteryl esterase activity assay
Biochem/physiol Actions
Cholesteryl palmitate is associated with atherosclerotic plaque. Deuterated cholesteryl palmitate in used in reconstituting high-density lipoprotein (HDL). An elevated levels of the ratio of cholesteryl oleate to cholesteryl palmitate is implicated with apoptotic cell death in the atherosclerotic lesions.
Packaging
5 mL Amber Glass Screw Cap Vial (700149P-10mg)
5 mL Amber Glass Screw Cap Vial (700149P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Regulatory Information
美国出口管控产品
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Suming Chen et al.
Journal of circulating biomarkers, 8, 1849454419879848-1849454419879848 (2019-10-22)
There is a wide variety of extracellular vesicles (EVs) that differ in size and cargo composition. EVs isolated from human plasma or serum carry lipid, protein, and RNA cargo that provides insights to the regulation of normal physiological processes, and
Mithilesh Kumar Jha et al.
Glia, 68(1), 161-177 (2019-08-28)
Schwann cell (SC)-specific monocarboxylate transporter 1 (MCT1) knockout mice were generated by mating MCT1 f/f mice with myelin protein zero (P0)-Cre mice. P0-Cre+/- , MCT1 f/f mice have no detectable early developmental defects, but develop hypomyelination and reduced conduction velocity
Matias M Vazquez et al.
Redox biology, 36, 101591-101591 (2020-06-13)
Macrophages play a pivotal role in the early stages of atherosclerosis development; they excessively accumulate cholesterol in the cytosol in response to modified Low Density Lipoprotein (mLDL). The mLDL are incorporated through scavenger receptors. CD36 is a high-affinity cell surface
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 700149P-10MG | 04061835184958 |
| 700149P-25MG | 04061835184965 |