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Merck
CN

800812P

Avanti

12:0 DG

Avanti Research - A Croda Brand

Synonym(s):

1,2-didodecanoyl-sn-glycerol; DG(12:0/12:0/0:0); 110611

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About This Item

Empirical Formula (Hill Notation):
C27H52O5
CAS Number:
Molecular Weight:
456.70
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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description

1,2-dilauroyl-sn-glycerol

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (800812P-10mg), pkg of 1 × 200 mg (800812P-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O([C@H](COC(=O)CCCCCCCCCCC)CO)C(=O)CCCCCCCCCCC

InChI

1S/C27H52O5/c1-3-5-7-9-11-13-15-17-19-21-26(29)31-24-25(23-28)32-27(30)22-20-18-16-14-12-10-8-6-4-2/h25,28H,3-24H2,1-2H3/t25-/m0/s1

InChI key

OQQOAWVKVDAJOI-VWLOTQADSA-N

General description

sn-1,2-diacylglycerols comprise short saturated acyl side chains (C4-C10) and 12:0 DG is also called 1,2-dilauroyl-sn-glycerol.

Application

12:0 DG has been used as an internal standard for spiking serum samples for liquid chromatography–mass spectrometry analysis. It may be used as an internal standard for spiking RAW 264.7 cells for mass spectroscopy studies and in reverse phase liquid chromatography coupled mass spectrometer for lipidomics studies of human plasma and serum samples.

Biochem/physiol Actions

1,2-dilauroyl-sn-glycerol is a polymerization initiator used in the synthesis of (R)-3-((2-bromo-2-methylpropanoyl)oxy)propane-1,2-diyl didodecanoate (BMPD). sn-1,2-diacylglycerols are prime regulators of biological functions especially in platelets. They also activate protein kinase C.

Packaging

5 mL Amber Glass Screw Cap Vial (800812P-10mg)
5 mL Amber Glass Screw Cap Vial (800812P-200mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Felicitas S Boretti et al.
Metabolomics : Official journal of the Metabolomic Society, 16(1), 1-1 (2019-12-05)
Food and dietary ingredients have significant effects on metabolism and health. To evaluate whether and how different diets affected the serum lipidomic profile of dogs. Sixteen healthy beagles were fed a commercial dry diet for 3 months (control diet). After an
Serum lipidome analysis of healthy beagle dogs receiving different diets
Boretti FS, et al.
Metabolomics, 16(1), 1-1 (2020)
Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm
Callender HL, et al.
Analytical Chemistry, 79(1), 263-272 (2007)



Global Trade Item Number

SKUGTIN
800812P-10MG04061835533824
800812P-200MG04061835533831