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Merck
CN

810153P

Avanti

16:0-06:0 NBD PE

Avanti Research - A Croda Brand

Synonym(s):

1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C33H56N5O11P
CAS Number:
Molecular Weight:
729.80
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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Product Name

16:0-06:0 NBD PE, Avanti Research - A Croda Brand 810153P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810153P-1mg), pkg of 5 × 1 mg (810153P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810153P

shipped in

dry ice

storage temp.

−20°C

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescently labeled lipid localized at the membrane interface. The molecule contains NBD label covalently linked to the headgroup of phosphatidylethanolamine. PE is mostly present in the brain and is the second most abundant, metabolically related aminophospholipid.

Application

16:0-06:0 NBD PE is suitable for the determination of enzyme substrate specificity of lipoteichoic acid synthase (LtaS).

Biochem/physiol Actions

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is involved in screening the effects of Red edge excitation shift (REES) experiment with the unique motional and dielectric property it possesses. PE functions as a substrate for a number of phospholipids of the cell membrane.

Packaging

5 mL Amber Glass Screw Cap Vial (810153P-1mg)
5 mL Amber Glass Screw Cap Vial (810153P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids



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Mirka E Wörmann et al.
Molecular microbiology, 79(3), 566-583 (2011-01-25)
Lipoteichoic acid (LTA) is an important cell wall polymer in Gram-positive bacteria. The enzyme responsible for polyglycerolphosphate LTA synthesis is LtaS, first described in Staphylococcus aureus. Four LtaS orthologues, LtaS(BS) , YfnI, YqgS and YvgJ, are present in Bacillus subtilis.
Maria Karatsa-Dodgson et al.
Journal of bacteriology, 192(20), 5341-5349 (2010-08-17)
Lipoteichoic acid (LTA) is an important cell wall component of Gram-positive bacteria. The key enzyme responsible for polyglycerolphosphate lipoteichoic acid synthesis in the Gram-positive pathogen Staphylococcus aureus is the membrane-embedded lipoteichoic acid synthase enzyme, LtaS. It is presumed that LtaS



Global Trade Item Number

SKUGTIN
810153P-1MG04061835185443