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About This Item
Empirical Formula (Hill Notation):
C33H56N5O11P
CAS Number:
Molecular Weight:
729.80
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
assay
>99% (TLC)
form
powder
packaging
pkg of 5 × 2 mg (810175P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidic acid (PA) is an amphipathic lipid containing a polar head group and two long hydrophobic acyl chains. PA is an anionic and a membrane structural lipid. It acts as a parent compound for more complex membrane phospholipids.
Application
18:1-06:0 NBD PA may be used for study the effects of NBD-PA induced vesiculation on epidermal growth factor receptor (EGFR) endocytosis in mammalian cells and the co-localization of fluorescently-labeled poly(A)-specific ribonuclease (PARN) with the NBD-tagged PA that outlines the close proximity phospholipase D (PLD2) and PARN.
Biochem/physiol Actions
Phosphatidic acid (PA) is a bioactive lipid and a secondary messenger. PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers respectively.
Packaging
5 mL Amber Glass Screw Cap Vial (810175P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
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Lipid second messengers and Receptors
Encyclopedia of Endocrine Diseases, 77(3), 329-334 (2004)
Bioactive Lipids
An Introduction to Biological Membranes, ,
number=(,
pages=), 453-478 (2016)
Karen M Henkels et al.
Oncotarget, 7(30), 47002-47017 (2016-06-04)
The intracellular concentration of the mitogen phosphatidic acid (PA) must be maintained at low levels until the need arises for cell proliferation. How temporal and spatial trafficking of PA affects its target proteins in the different cellular compartments is not
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 810175P-10MG | 04061835190065 |