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About This Item
Empirical Formula (Hill Notation):
C40H71N6O13P
CAS Number:
Molecular Weight:
875.00
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Product Name
16:0-12:0 NBD PS, Avanti Research™ - A Croda Brand 810193C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810193C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810193C
concentration
1 mg/mL (810193C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
Phosphoserine (PS) is present in the intracellular membranes and grey matter, and isenriched in the cytosolic leaflet of plasma membrane. NBD PS is a fluorescently labelled lipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.
Application
16:0-06:0 NBD PS or 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) may be used in the liposome preparation for in vitro assay of the phosphatidylethanolamine (PE) production by determining the phosphatidylserine decarboxylase 1 (Psd1p) activity.
Biochem/physiol Actions
Phosphatidylserine (PS) regulates numerous enzymes and structural components maintains the nerve cell membrane and myelin sheath.
Packaging
5 mL Amber Glass Screw Cap Vial (810193C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
Regulatory Information
危险化学品
易制毒化学品（2类）
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Yasushi Tamura et al.
The Journal of biological chemistry, 287(52), 43961-43971 (2012-11-06)
Phosphatidylethanolamine (PE) plays important roles for the structure and function of mitochondria and other intracellular organelles. In yeast, the majority of PE is produced from phosphatidylserine (PS) by a mitochondrion-located PS decarboxylase, Psd1p. Because PS is synthesized in the endoplasmic
Ouma Onguka et al.
The Journal of biological chemistry, 290(20), 12744-12752 (2015-04-02)
Phosphatidylethanolamine (PE) is a major cellular phospholipid that can be made by four separate pathways, one of which resides in the mitochondrion. The mitochondrial enzyme that generates PE is phosphatidylserine decarboxylase 1 (Psd1p). The pool of PE produced by Psd1p
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 810193C-1MG | 04061837666711 |