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About This Item
Empirical Formula (Hill Notation):
C62H94N3O14P
CAS Number:
Molecular Weight:
1136.40
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Product Name
18:1 PE CF, Avanti Research™ - A Croda Brand
assay
>99% (TLC)
form
solution
packaging
pkg of 1 × 1 mL (810332C-1mg), pkg of 5 × 1 mL (810332C-5mg), pkg of 5 × 2 mL (810332C-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
1 mg/mL (810332C-10mg), 1 mg/mL (810332C-1mg), 1 mg/mL (810332C-5mg)
lipid type
fluorescent lipids
shipped in
dry ice
storage temp.
−20°C
General description
Phosphoethanolamine (PHOS) is a precursor to phosphatidylcholine and phosphatidylethanolamine. 18:1 PE CF is a green fluorescent tagged phosphatidylethanolamine.
Application
18:1 PE CF may be used:
- to spike human serum
- to prepare concentrated lipid mix, PC:PE:fluoPE to assess basal binding properties and PC:PE:fluoPE:PIP to assess specific binding properties of the protein to each phosphoinositides (PIP)
- to prepare the large unilamellar vesicles (LUVs)
- in the preparation of fluorescent phosphoinositide?containing liposomes
- for fluorescent labeling of total lipids to the initial liposome formulation mixture
- in the formulation of pegylated magneto-liposomes (MLs) and transferrin (Tf) embedding
Biochem/physiol Actions
Phosphatidylethanolamine controls the membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1).
Packaging
5 mL Amber Glass Screw Cap Vial (810332C-10mg)
5 mL Amber Glass Screw Cap Vial (810332C-1mg)
5 mL Amber Glass Screw Cap Vial (810332C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Regulatory Information
危险化学品
易制毒化学品（2类）
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Protein-Lipid Interaction by Fluorescence (PLIF) to Characterize and Screen for Inhibitors of Protein-Phosphoinositide Interactions
Ceccato L, et al.
Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.], 89(1), 19-31 (2017)
Liposome Flotation Assays for Phosphoinositide-protein Interaction
Tronchere H and Boal F
Journal of Cell Science, 390(1), 1-13 (2015)
NUTS and BOLTS: applications of fluorescence-detected sedimentation
Kroe RR and Laue TM
Analytical biochemistry, 390(1), 1-13 (2009)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 810332C-5MG | 04061837667275 |
| 810332C-10MG | 04061837667251 |
| 810332C-1MG | 04061837667268 |