Skip to Content
Merck
CN

840029P

Avanti

18:0 PS

Avanti Research - A Croda Brand

Synonym(s):

1,2-dioctadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DSPS; PS(18:0/18:0); 110671

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C42H81NO10PNa
CAS Number:
Molecular Weight:
814.06
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


description

1,2-distearoyl-sn-glycero-3-phospho-L-serine (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840029P-10mg), pkg of 1 × 25 mg (840029P-25mg), pkg of 1 × 500 mg (840029P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1

InChI key

SJRBMGBLPUBGJL-MBAWARMDSA-M

General description

Phosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets.

Application

18:0 PS has been used to evaluate its affinity to cytochrome c using surface plasmon resonance (SPR) technique and in the preparation of phospholipid vesicles. It may be used in the preparation of polydimethylsiloxane (PDMS) hybrid microbubbles.

Biochem/physiol Actions

Phosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol.

Packaging

5 mL Amber Glass Screw Cap Vial (840029P-10mg)
5 mL Amber Glass Screw Cap Vial (840029P-25mg)
20 mL Clear Glass Screw Cap Vial (840029P-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Carolina Varela Chavez et al.
Cellular microbiology, 17(10), 1477-1493 (2015-04-18)
Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catalytic domain (TcsL-cat) into the cytosol upon an autoproteolytic process. TcsL-cat
German Stepanov et al.
FEBS letters, 583(1), 97-100 (2008-12-09)
We attempted to evaluate the affinity of the anionic phospholipids to cytochrome c by means of surface plasmon resonance (SPR) technique and to correlate it with the cytochrome c active site alterations and peroxidase activity. Our experiments showed a strong
Jung Yong Eum et al.
Journal of chromatography. A, 460849-460849 (2020-01-14)
Aging refers to the intracellular accumulation of reactive oxygen species that damages proteins, DNA, and lipids. As alterations in lipid metabolism may trigger metabolic disorders and the onset of metabolic diseases, changes in lipid profiles can be closely related to



Global Trade Item Number

SKUGTIN
840029P-10MG04061835228508
840029P-25MG04061835228515
840029P-500MG04061835228522