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840031P

Avanti

08:0 PS

Avanti Research™ - A Croda Brand

Synonym(s):

PS(8:0/8:0)

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About This Item

Empirical Formula (Hill Notation):
C22H41NO10PNa
CAS Number:
321862-88-8
Molecular Weight:
533.53
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

08:0 PS, 1,2-dioctanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840031P-10mg), pkg of 1 × 200 mg (840031P-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840031P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]

InChI

1S/C22H42NO10P.Na/c1-3-5-7-9-11-13-20(24)30-15-18(33-21(25)14-12-10-8-6-4-2)16-31-34(28,29)32-17-19(23)22(26)27;/h18-19H,3-17,23H2,1-2H3,(H,26,27)(H,28,29);/q;+1/p-1/t18-,19+;/m1./s1

InChI key

IOFLNDDTVDTSHA-VOMIJIAVSA-M

General description

Phosphatidylserine (PS), an acidic phospholipid is obtained from soybeans (soy-PS), bovine cortex (BC-PS) and synthetic derivation. It is mainly seen in animals, higher plants and microorganisms. It is localized in the inner leaflet of the plasma membrane.

Application

08:0 PS may be used as control anionic lipid to treat Xenopus eggs to study its effects on the fertilization events. It has also been used to form mixed micelles to study or compare the micellization behavior of mixed zwitterionic/cationic solutions and cationic gemini surfactants with that of 08:0 PS.

Biochem/physiol Actions

Phosphatidylserine (PS) can activate protein kinase C. It aids in removing apoptotic cells and also participates in platelet aggregation.

Packaging

20 mL Clear Glass Screw Cap Vial (840031P-200mg)
5 mL Clear Glass Sealed Ampule (840031P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Articles

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

Ryan C Bates et al.
Developmental biology, 386(1), 165-180 (2013-11-26)
We report a new step in the fertilization in Xenopus laevis which has been found to involve activation of Src tyrosine kinase to stimulate phospholipase C-γ (PLC-γ) which increases inositol 1,4,5-trisphosphate (IP3) to release intracellular calcium ([Ca](i)). Molecular species analysis
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

Global Trade Item Number

SKUGTIN
840031P-10MG04061835228553
840031P-200MG04061835228560