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840033P

Avanti

14:0 PS

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-ditetradecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DMPS; PS(14:0/14:0)

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About This Item

Empirical Formula (Hill Notation):
C34H65NO10PNa
CAS Number:
105405-50-3
Molecular Weight:
701.84
MDL number:
MFCD00077389
UNSPSC Code:
51191904
NACRES:
NA.25
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description

1,2-dimyristoyl-sn-glycero-3-phospho-L-serine (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840033P-10mg), pkg of 1 × 200 mg (840033P-200mg), pkg of 1 × 25 mg (840033P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C34H66NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-32(36)42-27-30(28-43-46(40,41)44-29-31(35)34(38)39)45-33(37)26-24-22-20-18-16-14-12-10-8-6-4-2;/h30-31H,3-29,35H2,1-2H3,(H,38,39)(H,40,41);/q;+1/p-1/t30-,31+;/m1./s1

InChI key

QSHQBWBFNCFHLO-MFABWLECSA-M

General description

Phosphatidylserine (PS) is a retinal phospholipid, which carries long-chain highly unsaturated fatty acyl groups.

Application

14:0 PS may be used as an internal standard for spiking serum lipid samples for liquid chromatography-mass spectroscopy analysis and as a component in the phospholipid monolayer to mimic model cancer cell membrane for the anticancer drug doxorubicin (DOx) interaction studies. It has been used in lipid binding assay to assess the binding of monoclonal antibodies (mAbs).

Biochem/physiol Actions

Phosphatidylserine (PS) helps to activate protein kinase C (PKC). It may possess anti-inflammatory properties. PS is also known to participate in tyrosine hydroxylase activation. It is also involved in the uptake of Ca2+ and glucose.

Packaging

5 mL Amber Glass Screw Cap Vial (840033P-10mg)
5 mL Amber Glass Screw Cap Vial (840033P-200mg)
5 mL Amber Glass Screw Cap Vial (840033P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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B Fichtl et al.
Langmuir : the ACS journal of surfaces and colloids, 34(16), 4914-4919 (2018-04-04)
Currently, biological signaling is envisaged as a combination of activation and movement, triggered by local molecular interactions and molecular diffusion, respectively. However, here, we suggest that other fundamental physical mechanisms might play an at least equally important role. We have
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Adherence of the fungus, Candida albicans, to biotic (e.g. human tissues) and abiotic (e.g. catheters) surfaces can lead to emergence of opportunistic infections in humans. The process of adhesion and further biofilm development depends, in part, on cell surface hydrophobicity
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Global Trade Item Number

SKUGTIN
840033P-200MG04061835228584
840033P-10MG04061835228577
840033P-25MG04061835228591