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Merck
CN

840045P

Avanti

Brain PI(4)P

Avanti Research - A Croda Brand

Synonym(s):

L-α-phosphatidylinositol-4-phosphate (Brain, Porcine) (ammonium Salt)

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About This Item

CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

Brain PI(4)P, Avanti Research - A Croda Brand 840045P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (840045P-1mg), pkg of 1 × 10 mg (840045P-10mg), pkg of 1 × 25 mg (840045P-25mg), pkg of 1 × 5 mg (840045P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 840045P

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C47H84O16P2.2H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)61-39(37-59-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-60-65(57,58)63-47-44(52)42(50)46(43(51)45(47)53)62-64(54,55)56;;/h11,13,17,19,22,24,28,30,39,42-47,50-53H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,57,58)(H2,54,55,56);2*1H3/b13-11-,19-17-,24-22-,30-28-;;/t39-,42+,43?,44?,45?,46?,47-;;/m1../s1

InChI key

HJHASIMOAXACIC-CVKYTLMISA-N

General description

Phosphatidylinositol 4-phosphate (PI4P) acts as a precursor of phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P2]. It is found in the membranes of Golgi apparatus.

Packaging

5 mL Clear Glass Sealed Ampule (840045P-10mg)
5 mL Clear Glass Sealed Ampule (840045P-1mg)
5 mL Clear Glass Sealed Ampule (840045P-25mg)
5 mL Clear Glass Sealed Ampule (840045P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids



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PI4P and PI (4, 5) P2 are essential but independent lipid determinants of membrane identity
Hammond GRV, et al.
Science, 337(6095), 727-730 (2012)
Dieter R Klopfenstein et al.
Molecular biology of the cell, 15(8), 3729-3739 (2004-05-25)
UNC-104 (KIF1A) is a kinesin motor that transports synaptic vesicles from the neuronal cell body to the terminal. Previous in vitro studies have shown that a Dictyostelium relative of UNC-104 transports liposomes containing acidic phospholipids, but whether this interaction is
Jitendra Kumar et al.
PLoS genetics, 6(11), e1001200-e1001200 (2010-11-17)
UNC-104/KIF1A is a Kinesin-3 motor that transports synaptic vesicles from the cell body towards the synapse by binding to PI(4,5)P(2) through its PH domain. The fate of the motor upon reaching the synapse is not known. We found that wild-type



Global Trade Item Number

SKUGTIN
840045P-10MG04061835351596
840045P-1MG04061835351602
840045P-25MG04061835351619
840045P-5MG04061835351626