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840857P

Avanti

16:0-18:1 PA

Avanti Research™ - A Croda Brand

Synonym(s):

1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); POPA; PA(16:0/18:1(9Z)); 110616

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About This Item

Empirical Formula (Hill Notation):
C37H70O8PNa
CAS Number:
169437-35-8
Molecular Weight:
696.91
MDL number:
MFCD00672609
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

16:0-18:1 PA, powder

description

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (840857P-200mg), pkg of 5 × 100 mg (840857P-500mg), pkg of 1 × 25 mg (840857P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1

InChI key

PPYXMAJBOKWTQX-RYRMQHSSSA-M

General description

Phosphatidic acid (PA), the smallest and simplest phospholipid is produced from phosphatidylcholine with the help of phospholipase D. This glycerophospholipid is an ester of glycerol, which possess two long-chain fatty acids (LCFAs) at C1 and C2 and phosphoric acid at C3 positions.

Application

16:0-18:1 PA is suitable for use
  • in liposomes preparation
  • for lipid extraction of mitochondria
  • to generate multilamellar phospholipid vesicles

Biochem/physiol Actions

Phosphatidic acid (PA) may induce negative curvature in the cytoplasmic leaflet of the plasma membrane, which enables the development of the hemi fusion intermediates, that is essential for the fusion of two membranes.

Packaging

5 mL Clear Glass Sealed Ampule (840857P-25mg)
5 mL Clear Glass Sealed Ampule (840857P-500mg)
5 mL Clear Glass Sealed Ampule (840857P-200mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Muscle Lipid Metabolism
Muscle and Exercise Physiology, 271-284 (2019)
Membrane polar lipids
Stillwell W
An Introduction to Biological Membranes: Composition, Structure and Function, 63-87 (2016)
Surfactant protein A (SP-A) binds to phosphatidylserine and competes with annexin V binding on late apoptotic cells
Jakel A, et al.
Protein & cell, 1(2), 188-197 (2010)
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Global Trade Item Number

SKUGTIN
840857P-25MG04061835229192
840857P-200MG04061835229185
840857P-500MG04061835229208