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Merck
CN

850141P

Avanti

16:0 PI

Avanti Research - A Croda Brand

Synonym(s):

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(16:0/16:0); DPPI; 110657

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About This Item

Empirical Formula (Hill Notation):
C41H82NO13P
CAS Number:
Molecular Weight:
828.06
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

16:0 PI, 1,2-dipalmitoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850141P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850141P-500ug))

manufacturer/tradename

Avanti Research - A Croda Brand 850141P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C41H79O13P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)51-31-33(32-52-55(49,50)54-41-39(47)37(45)36(44)38(46)40(41)48)53-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h33,36-41,44-48H,3-32H2,1-2H3,(H,49,50);1H3/t33-,36-,37-,38+,39-,40-,41-;/m1

InChI key

MRDHBHKPDFRCJQ-VGFLHHNXSA-N

General description

Phosphatidylinositol (PtdIns) is a structural phospholipid. PI is synthesized by mycobacteria and other bacterial genera in prokaryotes.
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Application

16:0 PI has been used as internal lipid standard for matrix-assisted laser desorption/ionization (MALDI)- fourier-transform ion cyclotron resonance (FTICR)- mass spectrometry (MS) and analysis. It is also suitable for use as an internal standard for mass spectrometric analyses.

Biochem/physiol Actions

Phosphatidylinositol (PI) participates in polyphosphoinositide turnover. It can be used as a substrate to produce several molecules, that can modulate various cellular functions. In eukaryotes, phosphatidylinositol (PI)-based lipids (phosphoinositides) plays a key role in intracellular signalling. It is also involved in the anchoring of glycosylphosphatidylinositol-linked proteins to the membrane.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850141P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850141P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Storage Class

11 - Combustible Solids



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Metabolic Heavy Isotope Labeling to Study Glycerophospholipid Homeostasis of Cultured Cells
Hanninen S, et al.
Bio-protocol, 7(9) (2017)
Phosphatidylinositol 4-Kinase from Bovine Brain
Methods in Neurosciences, 18, 93-99 (1993)
Phosphatidylinositol Turnover and Receptors
reference module in biomedical sciences (2016)



Global Trade Item Number

SKUGTIN
850141P-500UG04061835229468
850141P-100UG04061835229451