Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C45H94N3O19P3
CAS Number:
Molecular Weight:
1074.16
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
description
1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 μg (with stopper and crimp cap (850154P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850154P-500ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
General description
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2), a phosphoinositideinositol phospholipid is mainly present in the membranes of endosome and lysosome of fungi and higher eukaryotes.
Application
18:1 PI(3,5)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt)) may be used in vesicles for co-sedimentation assays. It has also been used:
- in lipid overlay assay
- in liposome co-sedimentation
- in liposome flotation assays
Biochem/physiol Actions
The level of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) surges in response to numerous extracellular stresses.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (850154P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850154P-500ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Sheena Claire Li et al.
Molecular biology of the cell, 25(8), 1251-1262 (2014-02-14)
Vacuolar proton-translocating ATPases (V-ATPases) are highly conserved, ATP-driven proton pumps regulated by reversible dissociation of its cytosolic, peripheral V1 domain from the integral membrane V(o) domain. Multiple stresses induce changes in V1-V(o) assembly, but the signaling mechanisms behind these changes
Markku Hakala et al.
The Journal of biological chemistry, 293(13), 4818-4829 (2018-02-10)
Membrane phosphoinositides control organization and dynamics of the actin cytoskeleton by regulating the activities of several key actin-binding proteins. Twinfilin is an evolutionarily conserved protein that contributes to cytoskeletal dynamics by interacting with actin monomers, filaments, and the heterodimeric capping
Bong-Kwan Han et al.
The Journal of biological chemistry, 288(28), 20633-20645 (2013-06-05)
Glucose/carbon metabolism is a fundamental cellular process in living cells. In response to varying environments, eukaryotic cells reprogram their glucose/carbon metabolism between aerobic or anaerobic glycolysis, oxidative phosphorylation, and/or gluconeogenesis. The distinct type of glucose/carbon metabolism that a cell carries
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 850154P-100UG | 04061835229611 |
| 850154P-500UG | 04061835229628 |