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850305C

Avanti

06:0 PC (DHPC)

Avanti Research™ - A Croda Brand

Synonym(s):

DHPC; 1,2-dicaproyl-sn-glycero-3-phosphocholine; PC(6:0/6:0)

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About This Item

Empirical Formula (Hill Notation):
C20H40NO8P
CAS Number:
34506-67-7
Molecular Weight:
453.51
MDL number:
MFCD00050431
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

06:0 PC (DHPC), 1,2-dihexanoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850305C-25mg), pkg of 2 × 20 mL (850305C-1g), pkg of 2 × 4 mL (850305C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850305C

concentration

10 mg/mL (850305C-25mg), 25 mg/mL (850305C-1g), 25 mg/mL (850305C-200mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OCC[N+](C)(C)C)OCC(OC(=O)CCCCC)COC(=O)CCCCC

InChI

1S/C20H40NO8P/c1-6-8-10-12-19(22)26-16-18(29-20(23)13-11-9-7-2)17-28-30(24,25)27-15-14-21(3,4)5/h18H,6-17H2,1-5H3

InChI key

DVZARZBAWHITHR-UHFFFAOYSA-N

General description

Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the tissues of animal. PCs are known to carry saturated and unsaturated fatty acids in the sn-1 and sn-2 position respectively.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

06:0 PC (1,2-dihexanoyl-sn-glycero-3-phosphocholine/DHPC) may be used:
  • in the preparation of lipid bicelles for nuclear magnetic resonance (NMR) experiments
  • to form lipid vesicles/micelles for guanosine triphosphate (GTP) hydrolysis (GTPase) assays
  • in the reconstitution of p7 protein of the hepatitis C virus (p7(5a)) in bicelles

Biochem/physiol Actions

Phosphatidylcholines (PCs) plays a functional role in reducing the level of blood lipid and cholesterol. It may also have the ability to inhibit cardiovascular disease and obesity.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850305C-1g)
5 mL Clear Glass Sealed Ampule (850305C-200mg)
5 mL Clear Glass Sealed Ampule (850305C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

易制毒化学品（2类）
危险化学品

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Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
Bhagavan NV, et al.
Essentials of Medical Biochemistry, 299-320 null
Mutagenesis and peptide analysis of the DRY motif in the alpha 2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors
Chung DA, et al.
Biochemical and biophysical research communications, 293(4), 1233-1241 null
Wen Chen et al.
Structure (London, England : 1993), 26(4), 627-634 (2018-03-20)
The p7 protein of the hepatitis C virus (HCV) can oligomerize in membrane to form cation channels. Previous studies showed that the channel assembly in detergent micelles adopts a unique flower-shaped oligomer, but the unusual architecture also presented problems for
View All Related Papers

Global Trade Item Number

SKUGTIN
850305C-25MG04061837791871
850305C-1G04061837791857
850305C-200MG04061837791864