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Merck
CN

850335C

Avanti

12:0 PC (DLPC)

Avanti Research - A Croda Brand

Synonym(s):

1,2-didodecanoyl-sn-glycero-3-phosphocholine; DLPC; PC(12:0/12:0)

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About This Item

Empirical Formula (Hill Notation):
C32H64NO8P
CAS Number:
Molecular Weight:
621.83
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

12:0 PC (DLPC), 1,2-dilauroyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850335C-25mg), pkg of 1 × 20 mL (850335C-500mg), pkg of 2 × 4 mL (850335C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850335C

concentration

10 mg/mL (850335C-25mg), 25 mg/mL (850335C-200mg), 25 mg/mL (850335C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@@H](OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3/t30-/m0/s1

InChI key

IJFVSSZAOYLHEE-PMERELPUSA-N

General description

The mucosal layer of the colon has phosphatidylcholine (PC). PCs carry fatty acids in the sn-1 and sn-2 positions, that are covalently attached to a glycerol through ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

12:0 PC (DLPC/1,2-dilauroyl-sn-glycero-3-phosphocholine) may be used as a standard to quantify phosphatidylcholine. It has also been used as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions.

Biochem/physiol Actions

Phosphatidylcholine (PC) has the ability to block the penetrance of bacteria by acting as a surfactant.

Packaging

5 mL Clear Glass Sealed Ampule (850335C-25mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850335C-500mg)
5 mL Clear Glass Sealed Ampule (850335C-200mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

易制毒化学品(2类)
危险化学品

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Articles

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn


Extraction and profiling of plant polar glycerol lipids
Liu Y and Wang X
Bio-protocol, 6, 1849e-1849e null
Comprehensive untargeted lipidomic analysis using core
Narvaaez R, et al.
Journal of Chromatography A, 1440, 123-134 null
Gina Valentino et al.
Pharmaceutics, 11(12) (2019-12-18)
The pivotal role of hepatic stellate cells (HSCs) in orchestrating the bidirectional process of progression and regression of liver fibrosis makes them an ideal target for exploring new antifibrotic therapies. Essential phospholipids (EPLs), with their polyenylphosphatidylcholine (PPC) fraction, either alone



Global Trade Item Number

SKUGTIN
850335C-25MG04061837792014
850335C-200MG04061837792007
850335C-500MG04061837792021