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About This Item
Empirical Formula (Hill Notation):
C19H42NO4P
CAS Number:
Molecular Weight:
379.51
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
MAPCHO™-14, n-tetradecylphosphocholine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (850338P-1g), pkg of 1 × 10 g (850338P-10g)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850338P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[P](=O)([O-])(OCC[N+](C)(C)C)OCCCCCCCCCCCCCC
InChI
1S/C19H42NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-23-25(21,22)24-19-17-20(2,3)4/h5-19H2,1-4H3
InChI key
BETUMLXGYDBOLV-UHFFFAOYSA-N
General description
MAPCHO™-14 is a fos-choline-based zwitterionic detergent.
Tetradecylphosphocholine is a structural analog of myristoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification. It has been used as a helper lipid for in vitro and in vivo gene transfer, and it has been shown to have some anticancer activity.
Application
MAPCHO™-14 has been used as a supplement in extraction buffer (RIPA buffer).
Biochem/physiol Actions
Fos-choline-14 (N-tetradecylphosphocholine) is mainly used for solubilization and purification of proteins.
Packaging
20 mL Clear Glass Screw Cap Vial (850338P-1g)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (850338P-10g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Brian L Cook et al.
PloS one, 3(8), e2920-e2920 (2008-08-07)
In order to begin to study the structural and functional mechanisms of olfactory receptors, methods for milligram-scale purification are required. Here we demonstrate the production and expression of a synthetically engineered human olfactory receptor hOR17-4 gene in a stable tetracycline-inducible
Study of a synthetic human olfactory receptor 17-4: expression and purification from an inducible mammalian cell line
Cook BL, et al.
Testing, 3(8), e2920-e2920 (2008)
Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1
Christensen PM, et al.
Faseb Journal, 30(6), 2351-2359 (2016)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 850338P-10G | 04061835230235 |
| 850338P-1G | 04061835230242 |