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About This Item
Empirical Formula (Hill Notation):
C34H68NO8P
CAS Number:
Molecular Weight:
649.88
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
13:0 PC, 1,2-ditridecanoyl-sn-glycero-3-phosphocholine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (850340P-200mg), pkg of 1 × 25 mg (850340P-25mg), pkg of 1 × 500 mg (850340P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850340P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCCC)=O)=O
InChI
1S/C34H68NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-33(36)40-30-32(31-42-44(38,39)41-29-28-35(3,4)5)43-34(37)27-25-23-21-19-17-15-13-11-9-7-2/h32H,6-31H2,1-5H3/t32-/m1/s1
InChI key
RLNYFMQMIIHWFV-JGCGQSQUSA-N
General description
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
13:0 PC is suitable for use:
- in the preparation of the giant unilamellar vesicles (GUVs)
- in the preparation of lipid monolayers
- as an internal standard for the extraction of total lipids from biological samples
Biochem/physiol Actions
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.
Packaging
20 mL Clear Glass Screw Cap Vial (850340P-500mg)
5 mL Amber Glass Screw Cap Vial (850340P-200mg)
5 mL Amber Glass Screw Cap Vial (850340P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
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Direct evidence that neural cell adhesion molecule (NCAM) polysialylation increases intermembrane repulsion and abrogates adhesion
Johnson CP, et al.
The Journal of Biological Chemistry, 280(1), 137-145 (2005)
Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation
Oskolkova OV, et al.
Journal of immunology (Baltimore, Md. : 1950), 185(12), 7706-7712 (2010)
Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles
Bagatolli LA and Gratton E
Biophysical Journal, 77(4), 2090-2101 (1999)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 850340P-200MG | 04061835230259 |
| 850340P-25MG | 04061835230266 |
| 850340P-500MG | 04061835230273 |