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About This Item
Empirical Formula (Hill Notation):
C44H76NO8P
CAS Number:
Molecular Weight:
778.05
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
Product Name
18:3 (Cis) PC, Avanti Research™ - A Croda Brand 850395C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850395C-25mg), pkg of 2 × 4 mL (850395C-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850395C
concentration
10 mg/mL (850395C-25mg), 25 mg/mL (850395C-200mg)
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
General description
18:3 (cis) PC or 1,2-dilinolenoyl-sn-glycero-3-phosphocholine is an unsaturated glycerophospholipid, with substitution of two chains of linolenic acid at sn-1 and sn-2 positions of the glycerol backbone, along with choline as a headgroup.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
18:3 (cis) PC or 1,2-dilinolenoyl-sn-glycero-3-phosphocholine:
- might be used in aqueous lipid-trehalose formulations to assess the long-term storage stability of lyophilized liposomes
- might be used in phospholipid monolayer to study the instability of unsaturated phospholipids at specified conditions
- has been used in aqueous sugar formulations or liposome formulations to characterize its degradation during lyophilization
Packaging
5 mL Clear Glass Sealed Ampule (850395C-200mg)
5 mL Clear Glass Sealed Ampule (850395C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
Regulatory Information
危险化学品
易制毒化学品（2类）
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N M Payton et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 85(2), 306-313 (2013-04-10)
As liquid liposomal formulations are prone to chemical degradation and aggregation, these formulations often require freeze drying (e.g., lyophilization) to achieve sufficient shelf-life. However, liposomal formulations may undergo oxidation during lyophilization and/or during prolonged storage. The goal of the current
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 850395C-200MG | 04061835227242 |
| 850395C-25MG | 04061835227259 |