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Merck
CN

850465P

Avanti

18:0-16:0 PC

Avanti Research - A Croda Brand

Synonym(s):

1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; SPPC; PC(18:0/16:0)

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About This Item

Empirical Formula (Hill Notation):
C42H84NO8P
CAS Number:
Molecular Weight:
762.09
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

18:0-16:0 PC, 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (850465P-200mg), pkg of 1 × 25 mg (850465P-25mg), pkg of 1 × 500 mg (850465P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850465P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H84NO8P/c1-6-8-10-12-14-16-18-20-21-23-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-22-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3/t40-/m1/s1

InChI key

BYSIMVBIJVBVPA-RRHRGVEJSA-N

General description

Phosphatidylcholine (PC), a phospholipid carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup.

Application

18:0-16:0 PC (1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
  • in bilayer membranes to study the thermodynamic properties of phase transitions
  • as a carrier in unilamellar vesicles to evaluate the fragmentation of hydroperoxy endoperoxide 13-HP-Endo-PC in a model membrane
  • as a lipid standard in liquid chromatography−mass spectrometry analysis

Biochem/physiol Actions

Phosphatidylcholine (PC) can serve as a surfactant in the mucus.

Packaging

20 mL Clear Glass Screw Cap Vial (850465P-500mg)
5 mL Amber Glass Screw Cap Vial (850465P-200mg)
5 mL Amber Glass Screw Cap Vial (850465P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Masaki Goto et al.
Biochimica et biophysica acta, 1778(4), 1067-1078 (2008-01-15)
The bilayer phase transitions of palmitoylstearoyl-phosphatidylcholine (PSPC), diheptadecanoyl-PC (C17PC) and stearoylpalmitoyl-PC (SPPC) which have the same total carbon numbers in the two acyl chains were observed by differential scanning calorimetry and high-pressure optical method. As the temperature increased, these bilayers
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features



Global Trade Item Number

SKUGTIN
850465P-200MG04061835230914
850465P-25MG04061835230921
850465P-500MG04061835230938