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About This Item
Empirical Formula (Hill Notation):
C21H42NO8P
CAS Number:
Molecular Weight:
467.53
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
08:0 PE, 1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (850699P-10mg), pkg of 1 × 25 mg (850699P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850699P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O
InChI key
UNACBKDVIYEXSL-LJQANCHMSA-N
General description
Phosphatidylethanolamine (PE) is a glycerophospholipid. This nonbilayer-forming phospholipid has a cone shape due to the presence of its head group.
Application
08:0 PE (1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine) may be used in the preparation of DOPC liposomes for pH sensor conjugation in imaging pH changes in living cells.
Biochem/physiol Actions
Phosphatidylethanolamine (PE) plays a vital role in the structure and function of eukaryotic membranes. It serves as a lipid chaperon. It is known to participate in the initiation of autophagy. The hexagonal phase of PE is involved in membrane fusion events.
Packaging
5 mL Clear Glass Sealed Ampule (850699P-10mg)
5 mL Clear Glass Sealed Ampule (850699P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
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Jungju Yoon et al.
Advanced materials (Deerfield Beach, Fla.), 26(26), 4559-4564 (2014-05-03)
Phase separation in films of phospholipids and conjugated polymers results in nanoassemblies because of a difference in the physicochemical properties between the hydrophobic polymers and the polar lipid heads, together with the comparable polymer side-chain lengths to lipid tail lengths
Federica Gibellini et al.
IUBMB life, 62(6), 414-428 (2010-05-27)
The glycerophospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE) account for greater than 50% of the total phospholipid species in eukaryotic membranes and thus play major roles in the structure and function of those membranes. In most eukaryotic cells, PC and PE
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 850699P-10MG | 04061835231027 |
| 850699P-25MG | 04061835231034 |