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858125P

Avanti

18:1 Lyso PG

Avanti Research™ - A Croda Brand

Synonym(s):

1-oleoy-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(18:1(9Z)/0:0); 110714

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About This Item

Empirical Formula (Hill Notation):
C24H46O9PNa
CAS Number:
326495-24-3
Molecular Weight:
532.58
MDL number:
MFCD00674367
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

18:1 Lyso PG, 1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder

assay

>99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)

form

powder

packaging

pkg of 1 × 1 g (858125P-1g), pkg of 5 × 100 mg (858125P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 858125P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C24H47O9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(28)31-19-23(27)21-33-34(29,30)32-20-22(26)18-25;/h9-10,22-23,25-27H,2-8,11-21H2,1H3,(H,29,30);/q;+1/p-1/b10-9-;/t22?,23-;/m1./s1

InChI key

STLDIXSFXILIFT-AXFOVFEGSA-M

General description

18:1 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are synthesized in γ-proteobacteria. They are non bilayer- forming lipids, present in very minute amounts.

Application

18:1 Lyso PG may be used:
  • for the preparation of liposomes
  • to determine the effects of phosphoglycerol(PG) and cardiolipin (CL) in F0F1 ATPase c subunit (F0-c) transformation
  • as an acyl acceptor to determine the substrate specificity of recombinant G0/G1 switch gene 2 (G0S2) for acyl acceptors

Biochem/physiol Actions

Lyso phosphoglycerol (Lyso PG) serves as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) for the synthesis of phosphoglycerol. Accumulation of lysophospholipids in bacterial membranes disturbs the membrane integrity due to its detergent-like physical property.

Packaging

5 mL Clear Glass Sealed Ampule (858125P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (858125P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class

11 - Combustible Solids

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Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2)
Zhang X, et al.
Faseb Journal, 33(5), 6655-6666 (2019)
Membrane insertion of F0 c subunit of F0F1 ATPase depends on glycolipozyme MPIase and is stimulated by YidC
Nishikawa H, et al.
Biochemical and Biophysical Research Communications, 487(2), 477-482 (2017)
Lipid bilayer modules as determinants of K+ channel gating
Syeda R, et al.
Test, 289(7), 4233-4243 (2014)
View All Related Papers

Global Trade Item Number

SKUGTIN
858125P-500MG04061835232277
858125P-1G04061835232260