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Merck
CN

860617P

Avanti

N-16:0 Phytosphingosine

Avanti Research - A Croda Brand

Synonym(s):

N-palmitoyl-phytosphingosine (Saccharomyces Cerevisiae)

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About This Item

Empirical Formula (Hill Notation):
C34H69NO4
CAS Number:
Molecular Weight:
555.92
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

N-16:0 Phytosphingosine, Avanti Research - A Croda Brand 860617P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860617P-10mg), pkg of 1 × 5 mg (860617P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860617P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO

InChI key

IVBULNXGVIHEKN-MVIDNBQJSA-N

General description

Phytosphingosine is a biologically significant saturated long-chain sphingoid base, found in membranes of yeasts, fungi, plants and mammalian epidermis, including the stratum corneum.

Application

N-16:0 Phytosphingosine has been used as a lipid standard in electrospray ionization (ESI)-mass spectrometry (MS)-based lipidomic analysis.

Biochem/physiol Actions

Phytosphingosine plays a vital role in the defense mechanism of the skin by exhibiting anti-microbial and anti-inflammatory properties. It elicits keratinocyte differentiation and is therefore, used as an active ingredient in the cosmetic formulations. PHS helps in maintaining the structural integrity of the membranes. It also regulates cellular growth and mediates the heat stress response of yeast.

Packaging

5 mL Amber Glass Screw Cap Vial (860617P-10mg)
5 mL Amber Glass Screw Cap Vial (860617P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Storage Class

11 - Combustible Solids

wgk

WGK 3



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Maria Makarova et al.
Current biology : CB, 30(3), 367-380 (2020-01-21)
Membrane function is fundamental to life. Each species explores membrane lipid diversity within a genetically predefined range of possibilities. How membrane lipid composition in turn defines the functional space available for evolution of membrane-centered processes remains largely unknown. We address



Global Trade Item Number

SKUGTIN
860617P-10MG04061835318643
860617P-5MG04061835318650