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Merck
CN

870205P

Avanti

16:0 PDP PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C45H80N2O9PNaS2
CAS Number:
Molecular Weight:
911.22
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

16:0 PDP PE, Avanti Research - A Croda Brand 870205P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (870205P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 870205P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(CCSSC1=CC=CC=N1)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C45H81N2O9PS2.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-32-44(49)53-39-41(56-45(50)33-28-26-24-22-20-18-16-14-12-10-8-6-4-2)40-55-57(51,52)54-37-36-46-42(48)34-38-58-59-43-31-29-30-35-47-43;/h29-31,35,41H,3-28,32-34,36-40H2,1-2H3,(H,46,48)(H,51,52);/q;+1/p-1/t41-;/m1./s1

InChI key

IUSHQKJFHVODPF-QUEDAWNRSA-M

General description

16:0 PDP PE, also referred as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio) propionate, belongs to a class of head group modified functionalized lipids. Functionalized lipids are primarily used as reporter molecules.

Application

16:0 PDP PE has been used in preparation of rhodamine high-density lipoprotein nanoparticle (Rh-HDL NP) synthesis.

Packaging

5 mL Amber Glass Screw Cap Vial (870205P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids

wgk

WGK 3



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Pathways for modulating exosome lipids identified by high-density lipoprotein-like nanoparticle binding to scavenger receptor type B-1
Angeloni NL, et al.
Scientific Reports, 6(1) (2016)
Nicholas L Angeloni et al.
Scientific reports, 6, 22915-22915 (2016-03-12)
Exosomes are produced by cells to mediate intercellular communication, and have been shown to perpetuate diseases, including cancer. New tools are needed to understand exosome biology, detect exosomes from specific cell types in complex biological media, and to modify exosomes.
Mariusz Kepczynski et al.
Biochimica et biophysica acta, 1858(10), 2362-2379 (2016-03-08)
Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as



Global Trade Item Number

SKUGTIN
870205P-25MG04061835192113