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About This Item
Empirical Formula (Hill Notation):
C28H58NO7P
CAS Number:
Molecular Weight:
551.74
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
C18-02:0 PC, Avanti Research™ - A Croda Brand 878114P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (878114P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 878114P
lipid type
bioactive lipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCCCC)=O
InChI
1S/C28H58NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h28H,6-26H2,1-5H3/t28-/m1/s1
InChI key
ZXCIEWBDUAPBJF-MUUNZHRXSA-N
General description
C18-02:0 PC, also referred as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine, is a natural platelet-activating factor. It is found in variety of cells including, basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets.
Application
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
Biochem/physiol Actions
C18-02:0 PC acts as a platelet-activating factor and facilitates platelet aggregation and secretion. It also plays a key role in inflammation and anaphylaxis.
Packaging
5 mL Clear Glass Sealed Ampule (878114P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
wgk
WGK 3
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Saki Yamaura et al.
Clinica chimica acta; international journal of clinical chemistry, 481, 184-188 (2018-03-20)
Measurement of lipoprotein-associated phospholipase A2 (Lp-PLA2) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 878114P-5MG | 04061835353866 |