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Merck
CN

880500P

Avanti

16:0 PEG550 PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] (ammonium salt)

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About This Item

CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

16:0 PEG550 PE, Avanti Research - A Croda Brand 880500P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (880500P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 880500P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C63H124NO22P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-61(65)83-58-60(86-62(66)31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)59-85-87(68,69)84-33-32-64-63(67)82-57-56-81-55-54-80-53-52-79-51-50-78-49-48-77-47-46-76-45-44-75-43-42-74-41-40-73-39-38-72-37

InChI key

VJMCGROHAQCSGJ-CSZVLRKSSA-N

General description

16:0 PEG550 PE is a polyethylene glycol (PEG) conjugated phospholipid. The molecular weight and exact mass are averages based on the polydispersity of PEG.

Biochem/physiol Actions

Polyethylene glycol (PEG) conjugated phospholipids are known to protect the steric nature of liposomes. Hence, they are commonly recommended for use in liposome formulation. PEGylated lipids are used as drug carriers. Use of highly concentrated PEG-lipids makes the possibility of mixed micelles.

Packaging

5 mL Clear Glass Sealed Ampule (880500P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids

wgk

WGK 3



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Sirkku Hanski et al.
Biomacromolecules, 11(12), 3440-3447 (2010-10-27)
We report on highly ordered oblique self-assemblies in ionic complexes of PEGylated triple-tail lipids and cationic polypeptides, as directed by side-chain crystallization, demonstrating also reversible oblique-to-hexagonal order-order transitions upon melting of the side chains. This is achieved in bulk by
Brian J Nablo et al.
Biophysical journal, 95(3), 1157-1164 (2008-07-23)
Nonelectrolyte polymers of poly(ethylene glycol) (PEG) were used to estimate the diameter of the ion channel formed by the Bacillus anthracis protective antigen 63 (PA(63)). Based on the ability of different molecular weight PEGs to partition into the pore and
G F Peacock et al.
Drug delivery, 10(1), 29-34 (2003-01-30)
A new cholesterol-carborane conjugate (BCH) has been synthesized as a potential targeting agent for boron neutron capture therapy (BNCT) of cancers. The compound is extremely water insoluble and was formulated in two liposomal formulations to determine if the compound could



Global Trade Item Number

SKUGTIN
880500P-25MG04061835192465