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880720P

Avanti

18:0 PEG1000 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (ammonium salt)

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About This Item

CAS Number:
474922-77-5
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

18:0 PEG1000 PE, Avanti Research™ - A Croda Brand 880720P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (880720P-200mg), pkg of 1 × 25 mg (880720P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880720P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C87H172NO32P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-85(89)117-82-84(120-86(90)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)83-119-121(92,93)118-37-36-88-87(91)116-81-80-115-79-78-114-77-76-113-75-74-112-73-72-111-71-70-110-69-68-109-67-6

InChI key

RMRFKOYDUNAYRA-NHGDJFPISA-N

General description

The molecular weight and exact mass are averages based on the polydispersity of polyethylene glycol (PEG).

Application

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (18:0 PEG1000 PE) might be used to prepare sterically stabilized liposome and study its characteristics by small-angle X-ray scattering (SAXS) method. It is also suitable for use in cholesterol-free, PEGylated (CF-PEG) liposomes to study its long term stability when loaded with a hydrophilic drug, carboplatin.

Biochem/physiol Actions

Phosphoethanolamine (PE) serves as a substrate for several phospholipids of the cell membrane. It is associated with phospholipid turnover. PE is also found to prevent tumor progression.

Packaging

5 mL Amber Glass Screw Cap Vial (880720P-200mg)
5 mL Amber Glass Screw Cap Vial (880720P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

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Brian J Nablo et al.
Biophysical journal, 95(3), 1157-1164 (2008-07-23)
Nonelectrolyte polymers of poly(ethylene glycol) (PEG) were used to estimate the diameter of the ion channel formed by the Bacillus anthracis protective antigen 63 (PA(63)). Based on the ability of different molecular weight PEGs to partition into the pore and

Global Trade Item Number

SKUGTIN
880720P-200MG04061835188222
880720P-25MG04061835188239