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About This Item
Empirical Formula (Hill Notation):
C39H69N3O8
CAS Number:
Molecular Weight:
707.98
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
pacFA GalCer, Avanti Research™ - A Croda Brand 900406P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (900406P-1mg), pkg of 1 × 5 mg (900406P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 900406P
lipid type
click reagents
shipped in
dry ice
storage temp.
−20°C
SMILES string
C#CCCCC1(N=N1)CCCCCCCCC(N[C@](CO[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)([H])[C@H](O)/C=C/CCCCCCCCCCCCC)=O
General description
The pacFA lipid contains a photoactivable diazirine ring with a clickable alkyne group.
Biochem/physiol Actions
D-galactosyl-β-1,1′ N-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-D-erythro-sphingosine (pacFA GalCer) may be used for a global analysis of protein-lipid interactions in living cells. pacFA acts as a precursor for the biosynthesis of bifunctional lipids. Proteins in contact with the bifunctional lipids are then cross-linked by ultraviolet (UV) irradiation of the diazirine ring. Finally, click chemistry is used to label the alkyne with a reporter molecule.
Packaging
5 mL Amber Glass Screw Cap Vial (900406P-1mg)
5 mL Amber Glass Screw Cap Vial (900406P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Regulatory Information
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In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids.
Per Haberkant et al.
Angewandte Chemie (International ed. in English), 52(14), 4033-4038 (2013-03-02)
Per Haberkant et al.
Biochimica et biophysica acta, 1841(8), 1022-1030 (2014-01-21)
Understanding biological processes at the mechanistic level requires a systematic charting of the physical and functional links between all cellular components. While protein-protein and protein-nucleic acid networks have been subject to many global surveys, other critical cellular components such as
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 900406P-1MG | 04061835188642 |
| 900406P-5MG | 04061835188659 |