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LM2312

Avanti

Sphingomyelin (d18:1/12:0)

Avanti Research - A Croda Brand

Synonym(s):

N-(dodecanoyl)-sphing-4-enine-1-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C35H71N2O6P
CAS Number:
Molecular Weight:
646.92
NACRES:
NA.25
UNSPSC Code:
12352211
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assay

>99% (TLC)

form

ethanol solution

packaging

pkg of 1 × 1 mL (LM2312-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C35H71N2O6P/c1-6-8-10-12-14-16-17-18-19-21-22-24-26-28-34(38)33(32-43-44(40,41)42-31-30-37(3,4)5)36-35(39)29-27-25-23-20-15-13-11-9-7-2/h26,28,33-34,38H,6-25,27,29-32H2,1-5H3,(H-,36,39,40,41)/b28-26+/t33-,34+/m0/s1

InChI key

HZCLJRFPXMKWHR-FEBLJDHQSA-N

General description

Sphingomyelin is one of the bioactive lipids found in plasma membrane.

Application

Sphingomyelin (d18:1/12:0) or N-(dodecanoyl)-sphing-4-enine-1-phosphocholine has been used as a lipid standard for phospholipid quantification by mass spectroscopy (MS) analysis.

Biochem/physiol Actions

Sphingomyelin (d18:1/12:0) or N-(dodecanoyl)-sphing-4-enine-1-phosphocholine serves as a substrate for sphingomyelinase.

Packaging

2 mL Amber Glass Sealed Ampule (LM2312-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.


pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

55.4 °F - closed cup

flash_point_c

13.0 °C - closed cup

Regulatory Information

危险化学品

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Ali Assi et al.
Analytical and bioanalytical chemistry, 412(3), 777-793 (2019-12-21)
Stratum corneum lipids are responsible for the skin's barrier function. They are the final product of epidermis lipid biosynthesis. During this process, lipids evolve from simple to complex structures in three main levels respectively (stratum basal level, stratum granulosum level
Nesli-Ece Sen et al.
International journal of molecular sciences, 20(23) (2019-11-27)
Ataxin-2 (human gene symbol ATXN2) acts during stress responses, modulating mRNA translation and nutrient metabolism. Ataxin-2 knockout mice exhibit progressive obesity, dyslipidemia, and insulin resistance. Conversely, the progressive ATXN2 gain of function due to the fact of polyglutamine (polyQ) expansions
Donato A Rivas et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 310(7), R561-R569 (2016-01-15)
The loss of skeletal muscle mass is observed in many pathophysiological conditions, including aging and obesity. The loss of muscle mass and function with aging is defined as sarcopenia and is characterized by a mismatch between skeletal muscle protein synthesis



Global Trade Item Number

SKUGTIN
LM2312-1EA04061837669804