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N-049

(±)-Norsertraline hydrochloride solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16H16Cl3N
CAS Number:
91797-57-8
Molecular Weight:
328.66
NACRES:
NA.24
PubChem Substance ID:
329818438
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD08063707
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grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

N[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C3=C1C=CC=C3.[H]Cl

InChI

1S/C16H15Cl2N.ClH/c17-14-7-5-10(9-15(14)18)11-6-8-16(19)13-4-2-1-3-12(11)13;/h1-5,7,9,11,16H,6,8,19H2;1H/t11-,16-;/m0./s1

InChI key

YKXHIERZIRLOLD-RISSCEEYSA-N

General description

Norsertraline is a major urinary metabolite and N-desmethyl analog of the SSRI antidepressant sertraline. Marketed under trade names such as Zoloft® and Lustral, sertraline is used to treat major depressive, obsessive-compulsive and panic and social anxiety disorders in both adults and children.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Zoloft is a registered trademark of Pfizer, Inc.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

危险化学品

This item has

Certificates of Analysis (COA)

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Victor L Serebruany et al.
The American journal of psychiatry, 162(6), 1165-1170 (2005-06-04)
In a platelet/endothelial biomarker substudy of the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART), the authors sought to determine whether plasma levels of sertraline and its primary metabolite N-desmethylsertraline affect the release of platelet/endothelial biomarkers. Fifty-five acute coronary syndrome patients
V L Serebruany et al.
Pharmacological research, 43(5), 453-462 (2001-06-08)
Recently, clinical depression has been identified as an independent risk factor for increased mortality in patients following acute coronary events. Although the underlying mechanisms of this link remain uncertain, increased platelet activity has been suggested but never proven as the
Bryan W Brooks et al.
Environmental toxicology and chemistry, 24(2), 464-469 (2005-02-22)
Increasing evidence indicates widespread occurrence of pharmaceuticals and personal care products (PPCPs) in municipal effluent discharges and surface waters. Studies that characterize the fate and effects of PPCPs in aquatic systems are limited, and to our knowledge, data regarding pharmaceutical
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Global Trade Item Number

SKUGTIN
N-049-1ML04061834081654