03-0184-00
SMC® Human Phospho-Tau (T181) High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human phospho-Tau (T181) in human serum, plasma, and cerebrospinal fluid (CSF)
Synonym(s):
pTau T181 Single Molecule Counting Kit, pTau T181 immunoassay kit, pTau T181 ultra-sensitive immunoassay, pTau Thr181 immunoassay kit
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About This Item
Product Name
SMC® Human Phospho-Tau (T181) High Sensitivity Immunoassay Kit,
Quality Level
description
Used for ultrasensitive quantification of Human phospho-Tau (T181) in human serum, plasma, and cerebrospinal fluid (CSF)
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
technique(s)
single molecule counting: suitable
input
serum
cerebrospinal fluid (CSF)
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
General description
Elevated levels of phospho Tau 181 in cerebrospinal fluid (CSF) serve as a biomarker for neurodegeneration, particularly in Alzheimer′s disease, where its presence correlates with disease severity and progression. Additionally, phospho Tau 181 contributes to neuroinflammation by activating glial cells, which can exacerbate neuronal damage and promote disease progression.
Application
Features and Benefits
- Ultrasensitive Detection: Enables femtogram-level measurement of pTau181 in serum, plasma or CSF.
- Enhanced Signal Resolution: Expanded dynamic range with improved signal-to-noise ratio ensures consistent and accurate assay results.
- Intuitive Assay Format: Leverages a straightforward sandwich immunoassay design for high-sensitivity detection.
- Automation-Friendly Design: Engineered for integration with automated liquid handling platforms, streamlining workflows and minimizing manual intervention.
- Specialized Scientific Support: Backed by expert teams with deep experience in SMC® assay technology.
Packaging
Analysis Note
- Sensitivity: LLOQ 940 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 230-240,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 96% Plasma: 130% CSF: 138%
- Recovery: Serum: 102% Plasma: 97% CSF: 91%
Other Notes
Legal Information
Disclaimer
signalword
Danger
target_organs
Respiratory Tract
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
Regulatory Information
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通过适合的免疫检测产品，探索神经免疫和神经炎症细胞因子及神经退行性疾病生物标志物。
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 03-0184-00 | 04061841929925 |