05-730
Anti-STEP Antibody, clone 23E5
clone 23E5, Upstate®, from mouse
Synonym(s):
Neural-specific protein-tyrosine phosphatase, PTPN5
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
23E5, monoclonal
Application:
IHC, IP, WB
Citations:
5
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
23E5, monoclonal
species reactivity
mouse, rat, human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PTPN5(84867)
General description
~64-66 (doublet) & 46
Immunogen
Peptide corresponding to amino acids 57-74 of rat STEP46
Application
Anti-STEP Antibody, clone 23E5 is an antibody against STEP for use in IP, WB, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Neurodegenerative Diseases
Ion Channels & Transporters
Neurodegenerative Diseases
Biochem/physiol Actions
STEP61, STEP46, STEP38 and STEP20
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Purified
Preparation Note
2 years at -20°C
Analysis Note
routinely evaluated by immunoblot on in RIPA lysates from whole rat brain preparations
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures.
Lombroso, P J, et al.
The Journal of Neuroscience, 13, 3064-3074 (1993)
Jun Chen et al.
The European journal of neuroscience, 29(2), 287-306 (2009-02-10)
Although the mechanisms underlying striatal neurodegeneration are poorly understood, we have shown that striatal pathogenesis may be initiated by high synaptic levels of extracellular dopamine (DA). Here we investigated in rat striatal primary neurons the mobilization of the mitogen-activated protein
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 05-730 | 04053252404474 |