06-207
Anti-Lyn Antibody
serum, Upstate®
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
15
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... LYN(4067)
General description
53 and 56kDa
Immunogen
peptide (NKQQRPVPESQL-LPGQRFQT) corresponding to residues 39-58 of human Lyn
Application
Anti-Lyn Antibody detects level of Lyn & has been published & validated for use in IP & WB.
Biochem/physiol Actions
two known forms of human Lyn
Physical form
whole antiserum containing 0.05% sodium azide
Analysis Note
Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on RIPA lysates from human A431 cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts.
Mirela Goldenberg-Furmanov, Ilan Stein, Eli Pikarsky, Hila Rubin, Shafika Kasem et al.
Cancer Research null
Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G protein signaling
Wan, Y., et al
The Journal of Biological Chemistry, 272, 17209-17215 (1997)
B M Vonakis et al.
The Journal of biological chemistry, 272(38), 24072-24080 (1997-09-20)
Aggregation of the high affinity receptor for IgE (FcepsilonRI) leads to the phosphorylation of tyrosines on the beta and gamma chains of the receptor by the Src family kinase Lyn. We have studied the interaction between Lyn and the FcepsilonRI
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 06-207 | 04053252589003 |