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Merck
CN

1.08382

Tris Base

solid, ACS reagent, reag. Ph. Eur., GR for analysis buffer substance

Synonym(s):

Tris Base, Tris(hydroxymethyl)aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol

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About This Item

Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
UNSPSC Code:
12161703
EC Index Number:
201-064-4
NACRES:
NA.05
Beilstein/REAXYS Number:
741883
MDL number:
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Product Name

Tris(hydroxymethyl)aminomethane, GR for analysis buffer substance ACS,Reag. Ph Eur

grade

ACS reagent

Quality Level

agency

reag. Ph. Eur.

vapor pressure

0.0267 hPa ( 20 °C)

form

solid

potency

>5000 mg/kg LD50, oral (Rat), >5000 mg/kg LD50, skin (Rat)

pH

10.2-10.6 (20 °C, 6 g/L in H2O)

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.), 219-220 °C/13.3 hPa

mp

167-172 °C (lit.)

solubility

678 g/L

density

1.35 g/cm3 at 23 °C

bulk density

840 kg/m3

storage temp.

15-25°C

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

General description

Biological buffer substance
Tris is widely used as a biological buffer substance in the pH range of 7-9. For example it is used for the freezing of proteins. The grade conforms precisely with the Reag. Ph. Eur. requirements.
GR for analysis buffer substance ACS,Reag. Ph Eur

Application

Tris(hydroxymethyl)aminomethane GR for analysis buffer substance ACS,Reag. Ph Eur. CAS 77-86-1, EC 201-064-4, chemical formula H₂NC(CH₂OH)₃.


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
108382100004022536512778
108382010004022536103778
108382050004022536103785
108382250004022536103808
108382902504022536103822